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Synthesis of a glibenclamide cocrystal: full spectroscopic and thermal characterization Share: February 9, 2018 Synthesis of a glibenclamide cocrystal: full spectroscopic and thermal characterization A cocrystal of glibenclamide (GLB), an antidiabetic drug classified as type II compound according to the Biopharmaceutics ,...

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Request PDF on ResearchGate | Cocrystals, a long known but understudied class of crystalline solids, have attracted interest from crystal engineers and pharmaceutical scientists in the past decade and are now an integral part of the preformulation stage of drug development This is largely because....

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Pharmaceutical cocrystals: An overview - ScienceDirect

Pharmaceutical cocrystals are emerging as a new class of solid drugs with improved physicochemical properties, which has attracted increased interests from both industrial and academic researchers In this paper a brief and systematic overview of pharmaceutical cocrystals is provided, with particular focus on cocrystal design ,...

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Pharmaceutical Cocrystals - ScienceDirect

The stoichiometric ratio of API and cocrystal former in a pharmaceutical cocrystal is mostly simple (1:1, 1:2, 1:3 or vice versa) Cocrystals are not necessarily binary compounds, ternary and quarternary cocrystals are known Cocrystals can be divided into: cocrystal anhydrates, cocrystal hydrates (solvates), cocrystals of salts ,...

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